The gut microbiota and mental health

Moqbil Sara, Niedobylski Sylwiusz, Laszczak Katarzyna, Warchoł Konrad, Mikos Eryk. The gut microbiota and mental health. Journal of Education, Health and Sport. 2021;11(9):304-309. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.09.037 https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.09.037 https://zenodo.org/record/5515293 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.09.2021. Revised: 18.09.2021. Accepted: 18.09.2021. The gut microbiota and mental health Sara Moqbil, Sylwiusz Niedobylski, Katarzyna Laszczak, Konrad Warchoł, Eryk Mikos Sara Moqbil; 0000-0003-1230-1444 Sylwiusz Niedobyski; 0000-0001-7266-623X Katarzyna Laszczak; 0000-0002-5084-0273 Konrad Warchoł; 0000-0001-9467-680X Eryk Mikos; 0000-0003-0507-2882 Abstract INTRODUCTION AND PURPOSE Recent studies have shown that changes in the microbiome, probiotic and antibiotic supplementation, can significantly modulate various forms of neuropsychiatric disorders - such as depression, anxiety and stress-related disorders. There is growing body of evidence pointing to a bidirectional correlation along the brain-gut microbiota line. This axis is connected through endocrine, immune and neuronal pathways. The nerves that make up the enteric nervous system transmit modifications occurring in the gastrointestinal tract and through the vagus nerve to the central nervous system (1). The main purpose of this review is to update recent information on the correlation between the gut microbiota and mental health. STATE OF KNOWLEDGE Interactions between the gastrointestinal system and brain function have become an important field of psychiatric research in recent years. Probiotics are thought to be a potentially valuable player in the treatment of many neuropsychiatric disorders. However, the role of specific gut microbiota species in the development of these disorders remains unclear. CONCLUSIONS Increasing knowledge of the correlation between gut microbiota and mental health may improve the quality of treatment for patients with neuropsychiatric conditions. Further research on larger groups is needed to assess whether probiotics can modify altered psychological well-being and be integrated into current, conventional treatments. Key words: gut microbiota, mental healt