ANTIBODY RESPONSE OF COVID-19 VACCINATION IN PREGNANT WOMEN AND TRANS-PLACENTAL PASSAGE INTO CORD BLOOD

Introduction: Vaccination against infectious pathogens is one of the most impactful public health interventions, reducing global morbidity and mortality related to infection. Objectives: The main objective of the study is to find the antibody response of COVID-19 vaccination in pregnant women and trans-placental passage into cord blood. Material and methods: This cross-sectional study was conducted in Punjab Health Department during 2020 to 2021. The data was collected from 100 pregnant females who were done with COVID-19 vaccination before giving birth. Results: The data was collected from 100 pregnant females. Three of these women were also infected with SARS-CoV-2 near vaccination; a manual review of their symptoms indicated that they were more likely associated with the infection rather than the vaccine. None of the reports indicated prolonged fever or severe adverse reactions. Conclusion: It is concluded that women, BNT162b2 mRNA vaccination compared with no vaccination was associated with a significantly lower risk of SARS-CoV-2 infection. Interpretation of study findings is limited by the observational design