Structural and antimicrobial studies of some newly synthesized mixed ligand complexes of CoII, NiII, CuII and ZnII

Department of Chemistry, Institute of Basic Sciences, Dr. B. R. Ambedkar University, Khandari Road, Agra-282 002, Uttar Pradesh, India E-mail : dev_kumar26@indiatimes.com Manuscript received 12 March 2010, revised 19 July 2010, accepted 20 July 2010 Four new mixed ligand complexes of CoII, NiII, Cull and znII with 2-furylglyoxal-2-amino thiophenol (FGATP) and diphenyl amine-2-hydroxy-2'-carboxylic acid (DPHC) were synthesized and characterized by their melting point determination of recrystallised samples, running TLC for single spot, elemental analyses, molar conductance, magnetic measurements, IR, 1H NMR and UV spectral data. All the synthesized compounds were screened for antimicrobial activities against two bacteria, Escllerichia coli (gram -ve) and Staphylococcus aureus (gram + ve), and two fungi, Aspergillus niger and Aspergillus flavus. Metal complexes exhibit several fold increase in their antimicrobial activity in comparison to that of the constituting ligand fragments as determined by Serial Dilution Method