ASPECTS OF CLINICAL AND LABORATORY RESULTS OF HIV-INFECTED PATIENTS

Uhan V. V., Goydyk V. S., Goydyk N. S., Gozhenko A. I. ASPECTS OF CLINICAL AND LABORATORY RESULTS OF HIV-INFECTED PATIENTS. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2019;1(82):43-50. ISSN 0049-6804. DOI http://dx.doi.org/10.5281/zenodo.2639537 http://www.herald.com.ua УДК 616.98 : 578.828.6-074/-078 DOI http://dx.doi.org/10.5281/zenodo.2639537 ASPECTS OF CLINICAL AND LABORATORY RESULTS OF HIV-INFECTED PATIENTS Uhan V. V., Goydyk V. S., Goydyk N. S., Gozhenko A. I. State Enterprise "Ukrainian Research Institute of Transport Medicine of the Ministry of Health of Ukraine", Odessa National Medical University, e-mail: doctorvictor@ukr.net. Summary. Uhan V. V., Goydyk V. S., Goydyk N. S., Gozhenko A. I. ASPECTS OF CLINICAL AND LABORATORY RESULTS OF HIV-INFECTED PATIENTS. - State Enterprise "Ukrainian Research Institute of Transport Medicine of the Ministry of Health of Ukraine", Odessa National Medical University, e-mail: doctorvictor@ukr.net. HIV – infection is the most important medical and social problem in the world. In organism various viral, bacterial, fungal diseases develop and recur affected by immunodeficiency. Changes in a patient’s state result in the last stage of the disease – AIDS, during which opportunistic diseases and tumor processes are manifested. The objective. Analyze and identify aspects of clinical and laboratory results of HIV-infected patients. Methods and materials. We studied and examined clinical and laboratory indicators of 130 patients who underwent inpatient treatment at the Odessa Regional AIDS Prevention and Control Center. Results. Significant disturbances in homeostasis were found in HIV-infected patients (the concentration of total protein and albumin decreased, the number of red blood cells and hemoglobin decreased, ESR, the level of creatinine and urea increased, AST, ALT, LDH, amylase activity increased, hyponatremia occurred). Conclusion. The changes observed had a direct dependence on the absolute number of CD4 + T-lymphocytes and tendency to deterioraion. Key words: HIV infection, CD4+T-lymphocytes, clinical and laboratory indicators