Circadian rhythm of metabolism indicators in healthy people according to saliva study findings

Hryshko Yu. M., Gorbatch T. V., Gozhenko A. I. Circadian rhythm of metabolism indicators in healthy people according to saliva study findings. Journal of Education, Health and Sport. 2018;8(10):338-346. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1490639 http://ojs.ukw.edu.pl/index.php/johs/article/view/6306 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author(s) 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.10.2018. Revised: 19.10.2018. Accepted: 31.10.2018. CIRCADIAN RHYTHM OF METABOLISM INDICATORS IN HEALTHY PEOPLE ACCORDING TO SALIVA STUDY FINDINGS Yu. M. Hryshko, T. V. Gorbatch, A. I. Gozhenko State Enterprise Ukrainian Institute for Medicine of Transport of the Ministry of Health of Ukraine, Odesa Abstract In recent years, the concept of functional-metabolic continuum (FMС) has been formulated, which indicates the relatively constant nature of metabolism and its parameters in the intercellular environment. Thus, in its turn, is closely and adequately connected to the functional activity of organs and cells, thus forming a single system – the continuum. In addition, the functional activity of key low molecular weight antioxidants in the tissues and biological fluids of the body may, to a large extent, indicate the adaptive abilities and reactions at the level of the entire organism. One of the possible approaches to FMC study, depending on the physiological activity of the body, is to determine the parameters of metabolism and regulatory molecules relative to the daily rhythm, i.e., their comparison in the morning and in the evening, when the changes in the body over the day are observed, in other words, when there is an overall load. The aim of this research was to examine the circadian rhythm of FMC in healthy people according to saliva study findings. Thus, the obtained results, firstly, represent the existence of daily changes in FMC, and secondly, constitute a possible information channel that can be used to study these changes, to determine and compare indicators in the morning and evening about the functional activity of the body involving the regulatory systems. Key words: functional-metabolic continuum, circadian rhythm, metabolis