Microgram determination of ticlopidine hydrochloride in single pharmaceutical preparation by HPLC method

Department of Chemistry, University of Allahabad, Allahabad-211 002, Uttar Pradesh, India E-mail : prof.icshukla@rediffmail.com Manuscript received 9 July 2007, revised 5 September 2008, accepted 12 November 2008 A new HPLC method for the determination of ticlopidine in single and in their pharmaceutical preparations has been described. The method is based on reverse phase liquid chromatography using C-18 column and a suitable mobile phase. The detection is done at 220 nm. The now rate is adjusted at 1.0 mL/min and the linearity is established