COVID 19 vaccine induced glycaemic disturbances in DM2 -A Case Report

The possibility of disturbances in Blood Sugar (BS) levels of Diabetes Mellitus (DM2) patients, following vaccination for Covid 19, is suggested, but not proved. No documented proof that vaccination actually disturbs the BS, is lacking. This article presents the first documented case of disturbed blood sugar, in a patient with DM2, on insulin, following vaccination for Covid 19 (Covishield).It is observed that initially there is increased Insulin Resistance, (IR) resulting in hyperglycaemia, which is temporary, self-limiting and doesn’t call for any increase in insulin dosage.This is followed by a more critical period, when there is increased insulin sensitivity, requiring decrease the pre- vaccination dose of insulin, as the risk of hypoglycemia is observed, as in the case under consideration. Hence, close monitoring and titration of revised insulin dosage, is called for, using a glucometer, during this second phase. Ultimately, the BS and insulin sensitivity/IR, return to the pre-vaccination levels. These disturbances may not come to light, unless the BS, following Covid 19 vaccination, is closely monitored. It is not predictable as to, in whom these disturbances in BS might occurs, and why it does so. The above inferences drawn are based on objective interpretation of the, truthfully recorded observations, during the case study period