PROFILE OF UTERINE ENDOMETRIAL CARCINOMA IN A TEACHING HOSPITAL IN KERALA.

Aim:To evaluate various clinical and pathological features associated with endometrial cancer. Methods:A retrospective analysis conducted on 50 patients who were surgically staged and histopathologically proved to have endometrial cancer in Amala Institute of Sciences between January 2013 and December 2016. Results:The median age at detection was 60 years and more than half of the study population was overweight or obese. Nulliparity was not a risk factor. Diabetes mellitus and hypertension were significant risk factors affecting 52 % of the study population. Endometroid adenocarcinoma FIGO Stage 1 ; Grade 1 was the commonest type - however 42% showed deep myometrial invasion. Conclusion: The epidemiological factors affecting this Kerala population for development of endometrial carcinoma almost parallels that of developed nations. Commonest type of endometrial carcinoma encountered is Type 1 - overweight or obese woman in their late 50s or 60s with Diabetes and Hypertension as risk factors. More than 75% showed FIGO Stage 1 Grade 1 Endometroid type although deep invasion of myometrium was significantly more than that of other populations. This may affect long term survival and prognosis in this group of patients