Suplementary Figures Faz-Lopez et al

Figure S1. Collagen deposition. Paraffin sections of 4µm thick from lung tissue, were Masson´s Trichrome stained and observed in microscopy light. Images were photographed with the 20x objective at 7, 28 and 60 dpi in WT, STAT1-/-, and STAT6-/- mice and collagen deposition was evaluated. Figure S2. : M1 and M2 markers after macrophages. WT, STAT1-/- and STAT6-/- mice were treated either with PBS-liposomes or clodronate-liposomes intratracheally to deplete macrophages, before and after being infected with 500 L2 T. canis larvae. The animals were euthanized at 4 dpi, lungs cells were collected, and flow cytometry was used to determine M1 or M2 activation. Representative dot plots and their respective percentage of F4/80+CD86+ (a), F4/80+IL-4Rα+ (b) and F4/80+MMR+ (c) double-positive cells are shown. Each dot plot represents an individual mouse. One-way ANOVA and Tukey's multiple comparison test. *P