SOP for quantification of inflammatory protein in DBS using LC-MS/MS

A protocol for quantification of inflammatory proteins (SAA1, SAA2, SAA4, CRP, A1AT, A1AG), including their specific isoforms (SAA2alpha, SAA2beta, A1AT1, A1AG1, A1AG2), and the adaptive immune effector IGHA1 in dry blood spots via LC-(MRM)-MS.Research Infrastructure RECETOX RI (No LM2018121) financed by the Ministry of Education, Youth and Sports, and Operational Programme Research, Development and Innovation - project CETOCOEN EXCELLENCE (No CZ.02.1.01/0.0/0.0/17_043/0009632)