THE COMPARISON OF 1ST DOSE HYPOTENSION WITH ACE (CAPTOPRIL) IN NORMOVOLEMIC AND HYPOVOLEMIC PATIENTS WITH CARDIAC FAILURE

Angiotensin-converting enzyme inhibitors are preferred drugs in congestive heart failure. The incidence of congestive heart failure is increasing today. Objective: The aim of this study was to determine the incidence of first dose hypotension (captopril) with ACE inhibitors in patients with chronic heart failure (CHF). Place and Duration: In the Medical Units of Mayo Hospital, Lahore for one-year duration from January, 2018 to December, 2018. Methods: Hundreds of newly diagnosed or previously diagnosed but not ACE therapy patients with congestive heart failure were admitted to Medical Units of Mayo Hospital, Lahore. Statistical analysis using SPSS 18.0 was done. Results: Expressed as mean ± standard deviation. Each continuous parameter between the two groups, patients with hypovolemia / hyponatremia, and patients without hypovolemia / hyponatremia, was analyzed by unpaired two-tailed Student's t test. Conclusion: Congestive heart failure is a major problem and a common disease. ACE inhibitors have become the standard therapy for heart failure. Key words: Hypotension, heart failure, hypovolemia and normovolemic