Stuclies on 4-Thiazolidinones. Preparation and Antimicrobial Activity of α-Phenyl-2-(2/, 5/-dihydroxy-3'-bromophenyl)-3'-aryl-5'-carboxymethy 1-4-thiazolidinones, α -Methyl2-(2'-hydroxy-3'/-nitro-5',-,-benzyl) .. 3'-aryl-5'-H/carboxymethyl4-thiazolidinones and α -Methyl-2-(2'/-hydroxy-3'/-nitro-5'/-chlorophenyl)-3-aryl-5-H/carboxymethyl-4-thiazoliGlinones

Department of Chemistry, Saurashtra University, Rajkot-360 005 Manuscript received 17 April 1984, revised 26 August 1985, accepted 29 October 1985 4-Thiazolidinones have been prepared for better therapeutic activity by condensing thioglycolic acid and thiomalic acid with anils obtained from 2,5-dihydroxy-3-bromo­benzophenone and 2-hydroxy-3-nitro-5-methylchloroacetophenones. The constitution was supported by ir spectra and the products were tested for antimicrobial activity