PROSPECTIVE STUDY TO DETERMINE PREVALENCE OF H. PYLORI IN PATIENTS SUFFERING FROM NON-ULCER DYSPEPSIA

Objective: To determine H. pylori prevalence in patients suffering from non ulcer dyspepsia by doing rapid urease test, histopathology of gastric biopsy and serology. Place and duration: In the Medicine Unit II of Jinnah Hospital, Lahore for one year duration from March 2018 to March 2019. Methods: Rapid urease test, serology test and gastric biopsy histopathology for H. Pylori were performed in 50 patients with ulcer-like symptoms in both sexes but no evidence of peptic ulcer disease on gastroscopy. Results: H. Pylori was detected in gastric biopsy histopathology in 33 patients (66%). 95% CI was 51.14% to 78.41%. Serological test was positive in 36 patients (72%). 95% CI was 50.30% to 76.31%. In 35 patients (70%); rapid urease test was positive. The 95% confidence interval was 55.21% to 81.71%. Conclusion: Rapid urease test and serological test for H. Pylori may provide good diagnostic performance in subjects with non-ulcer dyspepsia in our inhabitants. Keywords: H. Pylori, non-ulcer dyspepsia, diagnosis