Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-ones as prospective antimicrobial agents

Several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) have been synthesized by conventional synthesis methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N) . Furthermore the synthesized 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) were tested for antimicrobial activities. The compound 4c displayed significant biological activities among the all tested derivatives