Relationships between geomagnetic Ар-indeх and HRV and endocrine parameters in patients with dysfunction of the neuroendocrine-immune complex

Tserkovniuk Ruslan, Gozhenko Anatoliy, Korolyshyn Tetyana, Ruzhylo Sofiya, Kikhtan Volodymyr, Fil Vitalij, Anchev Anatoliy, Zukow Walery, Yanchij Roman, Popovych Igor. Relationships between geomagnetic Ар-indeх and HRV and endocrine parameters in patients with dysfunction of the neuroendocrine-immune complex. Journal of Education, Health and Sport. 2021;11(11):295-303. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.11.029 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2021.11.11.029 https://zenodo.org/record/5859200 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.11.2021. Revised: 20.11.2021. Accepted: 30.11.2021. Relationships between geomagnetic Ар-indeх and HRV and endocrine parameters in patients with dysfunction of the neuroendocrine-immune complex Ruslan Tserkovniuk1, Anatoliy Gozhenko1, Tetyana Korolyshyn1,2,3, Sofiya Ruzhylo4, Volodymyr Kikhtan3, Vitalij Fil4, Anatoliy Anchev1, Walery Zukow5, Roman Yanchij2, Igor Popovych1,2 1Ukrainian Research Institute of Medicine for Transport, Odesa, Ukraine ruslan.urology@gmail.com prof.gozhenko@gmail.com 2OO Bohomolets’ Institute of Physiology, Kyїv, Ukraine i.popovych@biph.kiev.ua janchij2014@gmail.com 3Clinical sanatorium “Moldova”, Truskavets’, Ukraine 4Ivan Franko Pedagogical University, Drohobych, Ukraine doctor-0701@ukr.net fillvitalij@gmail.com 5Nicolaus Copernicus University, Torun, Poland w.zukow@wp.pl Abstract Background. Recently, on the example of two cohort of patients, we found that disturbances of the geomagnetic field cause a significant immediate modulating effect on the level of immune parameters in the blood. The data available in the literature give grounds for assumptions about the direct effect of disturbances of the geomagnetic field on immunocytes, and indirectly, through immunotropic neurotransmitters and hormones. Our hypothesis is as follows. Disturbances of the geomagnetic field are perceived by acupuncture points. The information obtained is transmitted to neurons and endocrinocytes, the mediators of which, in turn, affect immunocytes. The purpose of this study is to test this hypothesis. Material and methods. The object of observation were 21 men (24-63 y) and 20 women (30-72 y) with neuroendocrine-immune complex dysfunction. Each patient was tested twice with an interval of 4 days. Retrospectively we recorded the geomagnetic Ap-Index on the day of testing and during the previous 7 days, using resource https://www.spaceweatherlive.com/. Recorded the heart rate variability (HRV) parameters, determined the plasma level of cortisol, triiodothyronine and testosterone. Results. During the week, the average level of Ap-index ranged from 7 to 13 nT. Maximum coefficients of multiple correlation with HRV&Hormonal parameters were detected for Ap-index on 2 (R=0,506) and 7 (R=0,403) days before testing. The canonical correlation between Ap-indices for 7 days before and on the day of testing, and the HRV&Hormonal parameters is 0,766. In turn, the immune parameters are closely related to the HRV&Hormonal parameters (R=0,714). Conclusion. Disturbances of the geomagnetic field (Ap-index) causes a significant immediate modulating effect on the immune, HRV and endocrine parameters, apparently through acupuncture points as polymodal receptors of the ecoceptive sensitivity system. Key words: geomagnetic Ap-index, HRV, cortisol, triiodothyronine, testosterone, relationships, humans