EVALUATION OF IN-VITRO ANTI-MICROBIAL POTENTIAL OF THE NOVEL SIDDHA FORMULATION POOVARASUNEI AGAINST STAPHYLOCOCCUS AUREUS, STREPTOCOCCUS PYOGENES, CANDIDA ALBICANSAND ASPERGILLUS NIGER

Siddha medicines benefit the society in managing dreadful diseases since several centuries. People rely of Indian system of traditional medicines as it has wide range of therapeutic activity in management of several infectious diseases. Most prevailing problem in treating infectious diseases is resistance. Recently scientist had found that evolutionary pathway on microbes made them to adopt and become resistant to currently available marketed antibiotics. Till date in allopathic system of medicine there are very limited number of antibiotics are available for clinical management of several infectious disease. Still limitation prevails in using such antibiotics because of resistance, side effects and allergy etc. Hence the exploration of alternative therapy for the infectious disease grabs the attention of the siddha researchers and medicinal microbiologist as well. The main objective of the present study is to screen the antimicrobial potency of the siddha formulation PoovarasuNei (PN). The result of antimicrobial screening study clearly projects that the drug PN did not shown anti-microbial activity at the concentration of 100 to 300 µg against Streptococcus aureus, Candida albicans and Aspergillus Niger. Whereas the formulation PN shown significant activity against Staphylococcus pyogenes with the inhibition zone ranges from 2mm to 10mm at the concentration of 100 to 300 µg. From the study it was concluded that the drug PN was effective against Streptococcus pyogenesand has no anti-microbial property against Streptococcus aureus, Candida albicans and Aspergillus Niger and hence further study has to be carried out in higher concentration and also against other gram negative , positive and fungal species other than the tested one