Evaluation of Neonatal Cholestasis: An Experience in a Tertiary Centre of Bangladesh

ABSTRACT Background: A common presenting feature of neonatal hepatobiliary and metabolic dysfunction is cholestatic jaundice. Any infant who remains with jaundice beyond age 2 to 3 weeks must be assessed with fractionated serum bilirubin level. Late referral and lack of exact etiological diagnosis results in poor outcome in a substantial number of cases in Bangladesh. Objective: Retrospective evaluation of infants with cholestatic jaundice in terms of history, common clinical presentation and biochemical profile with etiologies. Materials & Methods: The study was conducted in the Department of Pediatric Gastroenterology, Hepatology & Nutrition, Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh from July 2014 to June 2016 on 80 infants who were presented with cholestatic jaundice at