Synthesis and Amoebicidal Activity of Some 2-Methyl-6(8)-alkyl-4-(arylsulphonylhydrazino)quinolines

Department of Chemistry, Lucknow University, Lucknow-226 007 Manuscript received 10 April 1981, revised 6 November 1981, accepted 11 March 1982 A series or substituted 4-(arylsulphonylhydrazino)quinolines have been synthesised for studying their amoebicidal activity. All the compounds were screened for amoebicidal activity against E. Histolytica. Contrary to expectations, no significant amoebicidal activity was observed when testing was done against the axenic culture or E. Histolytica at a concentration or 125 µg/ml