Population genomics reveals repeated signals of adaptive divergence in the Atlantic salmon of northeastern Europe

Our ability to examine genetic variation across entire genomes have enabled many studies searching for the genetic basis of local adaptation. These studies have identified numerous loci as candidates for differential local selection, however relatively few have examined the overlap among candidate loci identified from independent studies of the same species in different geographic areas or evolutionary lineages. We used an allelotyping approach with a 220K SNP array to characterize the population genetic structure of Atlantic salmon in northeastern Europe and ask whether the same genomic segments emerged as outliers among populations in different geographic regions. Genome-wide data recapitulated the phylogeographic structure previously inferred from mtDNA and microsatellite markers. Independent analyses of three genetically and geographically distinct groups of populations repeatedly inferred the same 17 haploblocks to contain loci under differential local selection. The most strongly supported of these replicated haploblocks had known strong associations with life history variation or immune response in Atlantic salmon. Our results are consistent with these genomic segments harbouring large-effect loci which have a major role in Atlantic salmon diversification and are ideal targets for validation studies.A ReadMe file is included with the datasets Funding provided by: Academy of FinlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002341Award Number: 302873Funding provided by: Academy of FinlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002341Award Number: 284941Funding provided by: Academy of FinlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002341Award Number: 314254See associated manuscript