Relationships between plasma levels of main adaptogene hormones and EEG & HRV parameters at human with dysadaptation

Korda, Mykhaylo, Gozhenko, Anatoliy, Fihura, Oksana, Popovych, Dariya, Żukow, Xawery, Popovych, Igor. Relationships between plasma levels of main adaptogene hormones and EEG & HRV parameters at human with dysadaptation. Journal of Education, Health and Sport. 2021;11(12):492-512. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.12.040 https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.12.040 https://zenodo.org/record/7032706 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 1 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 25.11.2021. Revised: 15.12.2021. Accepted: 31.12.2021. Relationships between plasma levels of main adaptogene hormones and EEG & HRV parameters at human with dysadaptation Mykhaylo M. Korda1, Anatoliy I. Gozhenko2, Oksana A. Fihura2,3, Dariya V. Popovych1, Xawery Żukow4, Igor L. Popovych2,5 1IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine cordamm@yahoo.com darakoz@yahoo.com 2Ukrainian Scientific Research Institute of Medicine of Transport, Odesa, Ukraine prof.gozhenko@gmail.com 3Ivan Franko State Pedagogical University, Drohobych, Ukraine oksanafigura08@gmail.com 4Medical University of Bialystok, Bialystok, Poland xaweryzukow@gmail.com 5Bohomolets’ Institute of Physiology of National Academy of Sciences, Kyїv, Ukraine i.popovych@biph.kiev.ua Abstract Background. The immunoneuroendocrinology became the foundation of the Truskavetsian Scientific School of Balneology. The focus of research was on the relationships between EEG and HRV parameters, EEG&HRV and leukocytogram, phagocytosis, cellular and humoral immunity as well as between changes in these parameters under the influence of adaptogenic factors Truskavets’ spa. The purpose of this study is relationships between plasma levels of major adaptogene hormones and EEG&HRV parameters at human with dysadaptation. Materials and Methods. The object of observation were 10 women 33-76 y and 10 men 37-67 y without a clinical diagnosis, but with the deviations from the norm in a number of parameters of the neuro-endocrine-immune complex as a manifestation of dysadaptation. Parameters of EEG and HRV as well as hormones levels before and after a one-week course of drinking of Naftussya bioactive water registered. Results. Using the method of canonical correlation analysis, it was found that the level of triiodothyronine is determined by the constellation of 17 EEGs and 4 HRVs parameters by 87,5%. The rate of determination of the cortisol level by 14 EEGs and 3 HRVs parameters is 83,7%, and aldosterone by the other 14 EEGs and 3 HRVs parameters is 80,0%. Neuromodulation of testosterone and calcitonin levels is characterized by sexual dimorphism. With the same coefficients of determination (92,4%), the regression model for testosteroneemia in women included 15 EEGs parameters and no HRV parameters, instead testosteroneemia in men is modulated by other 11 EEGs parameters and one HRV parameter. The level of calcitonin in women is determined by 86,2% by the constellation of 9 EEGs and 2 HRVs parameters, while in men by 83,5% by the other 5 EEGs and 4 HRVs parameters. Conclusion. Plasma levels of the main adaptation hormones are accompanied by specific patterns of EEG and HRV parameters. Keywords: EEG, HRV, Cortisol, Testosterone, Aldosterone, Triiodothyronine, Calcitonin, Male, Female, relationships