PATHOLOGICAL CHANGES OF BLOOD IN MALARIAL PATIENTS

Objectives: The study was conducted to analyze pathological changes associated with different types of malaria among adults. Methodology: The observational method of analysis was conducted for 133 malaria patients at Infectious Diseases Unit of Mayo Hospital Lahore. The study was conducted from January 2015 to December 2017. The malarial parasites were tested by using Leishman’s staining through thick and thin slides. The samples were examined by expert hematologist and full blood count was accomplished by using Beckman Coulter machine. Results: The sample consisted of thrombocytopenia (83%), anemia (64%), lymphopenia (24%) and monocytosis (10%). The parasites P. Falciparum was more prevalent as compared to P.Vivax which was (81%) in thrombocytopenia culture - p value >0.05. The percentage of anemia was (P. Falciparum 67% and P. Vivax 63% with a p value >0.05. Lymphopenia was slightly more different, 36% in Plasmodium. Vivaxcan and 15% in Plasmodium. Falciparum, with a p-value