ANTHELMINTIC ACTIVITIES OF STEM BARK OF PARKIA BIGLOBOSA ON WEST AFRICAN DWARF GOATS INFECTED WITH HAEMONCHUS CONTORTUS

The anthelmintic effects of stem bark extracts of Parkia biglobosa was evaluated on West African Dwarf (WAD) goats. The stem bark of the plant was obtained from Kwara state of Nigeria. The extraction was done and yielded Crude Methanol Stem Bark Extracts (CMSBE), Ethyl acetate (EA) fraction and Aqueous (AQ) fraction. The anthelmintic potentials were studied in vivo in 18 WAD goats in six completely randomised groups, A, B, C, D, E and F with three animals per group. Group A was treated with 5mL/kg of distilled water as negative control, group B with 6.25mg/kg of Albendazole (ABZ)(positive control), groups C and D with 1000mg/kg and 2000mg/kg of CMSBE respectively and groups E and F with 1000mg/kg of EA fraction and AQ fraction each respectively. Faecal samples were collected for two weeks after treatment to evaluate faecal egg counts. After 16th day, one animal was euthanized from each group to determined percentage deparasitization. The result from this study revealed that, the phytochemical constituents present in CMSBE were alkaloid, anthraquinones, cardiac glycosides, glycosides, flavonoids, oils, phlobatannins, reducing sugar, saponins, sterols/steroids, tannin (condensed and hydrolysable) and terpenoids. In vivo result showed significant (P