Clinicopathological Study of Toxoplasma Lymphadenitis in a Girl from Baghdad Province

Background: A wide spectrum of clinical features related to toxoplasma infection in human, the enlargement of lymph node are the most frequently observed clinical form of toxoplasma in human. Objective: This study was designated to confirm of toxoplasma infection by serological test, heamatological tests and histopathological examination of cervical palpable mass in a girl 18 years old. Patients and Methods: A young woman patient from Baghdad province is described in which the clinical presentation resembled unilateral cervical palpable mass arising from left lateral side of the neck below the ear with three month history of fever, night sweat, weakness, restless and loss of appetite. Blood sample obtained from the patient and white Blood count were performed using blood analyser for haematological test. Also serum was prepared for Serological test. Selective excisional biopsy of the swelling was taken for gross and hisopathological examination, preserved in 10% formalin, fixation and processing was routinely done, and staining with Haematoxylin and Eosin stain. Results: Hematological and serological results revealed the WBCs were 6.4 co3 /ml with mild eosinophilia, while serum sample showed strongly positive for anti Toxo IgM antibodies (63.5) which indicate acute toxoplasmosis. Surgical removal of the swelling appeared as enlarged lymph node consist of oval swelling measuring of 18 × 9 mm. Section showed whitish soft tissue with turbid fluid. Histopathological examination of the lymph node section showed reactive follicular lymphoid hyperplasia with irregular enlargement of germinal centre, other section showed cluster of proliferated epitheliod histeocytes with thickening of trabeculi and ovoid structure in epitheliod histeocytes containing trophozoites appeared within germinal centre and areas of necrosis were observed in other section. Conclusion: Acute toxoplasma lymphadenitis recognized by clinical signs, result of serological test and gross with histopathological examination.International Journal of Clinical and Medical Cases (ISSN:2517-7346