Loop electrosurgical excision procedure in Greek patients with vulvar intraepithelial neoplasia

Objective: The aim of our study was to evaluate the therapeutic effectiveness of loop electrosurgical excision procedure (LEEP) in Greek patients with vulvar intraepithelial neoplasia (VIN). Materials and Methods: Between January 2002 and January 2009, about 55 women with histologically confirmed VIN usual type were included in our study. For LEEP procedure we used a high frequency Electrosurgery Unit with at least 80 W output. The tissue was removed to the 2nd surgical plane. Statistical analyses were performed using the SPSS-13 for Windows. Results: Complete response rate, at 12 months of follow up, was 100%. Complete response rate, at 48 months of follow up, was 80%. Recurrence rate, at 48 months of follow up, was 20%. Conclusion: LEEP may constitute a valuable excisional method for the treatment of VIN. It provides an interpretable specimen of the whole lesion within a few minutes. It needs a short period of training and has low cost