SENSITIVITY AND PATTERN OF MICROORGANISMS CAUSING URINARY TRACT INFECTION

Objective: To determine the patterns and susceptibility of pathogens causing urinary tract infection in a tertiary hospital. Study Design: A Prospective study. Place and duration: In the Urology department of Fatima Memorial Hospital, Lahore in collaboration with Pathology department for one year duration from November 2017 to November 2018. Methods: By an international standard method; all samples were analyzed under the qualified microbiologist supervision. Susceptibility to antibiotics of the microorganisms isolated was tested for antibiotics used commonly by Kirby Baur technique. Results: 458 total samples were sent from the accepted patients during the study period. Mean bacteriuria in (73.14%) 335 samples, 100 samples (21.8%) were sterile and in 23 samples (5.02%) insignificant bacteriuria was noted. In 297 (64,41%) samples E. coli was the most common pathogens isolated, Enterobacter and Klebseilla Spp in each sample in (11,31%)51 samples, 36 (7.8%) samples Proteus was isolated, Pseudomonas was noted in 15 (3.27%) samples and (1.74%) 8 samples were of Citrobacter. Conclusion: 73% of the samples have significant growth. In suspected UTI cases; there was high yield of good clinical relationship in positive cultures. In urine cultures; gram negative rods were the isolated organisms. One analysis shows that urinary tract infections causing pathogens develop resistance to antibiotics used commonly. Key words: Antibiotics, Urinary tract infection, microorganisms, susceptibility bacteriuria