Prospective study of the association of coagulopathy and isolated traumatic brain injury

ABSTRACT The purpose of this study is to evaluate the association of coagulopathy and isolated traumatic brain injury as regard its frequency and outcome for patients who developed coagulopathy. This prospective study was conducted to include sixty patients with isolated traumatic brain injury admitted to attending the Emergency Department of Alexandria main university hospital. Primary survey and secondary survey done for those patients, radiological investigations done including CT brain and other radiological investigations to exclude other sources of coagulopathy. This also includes laboratory tests to asses coagulation as INR, platelet count, PTT and FDP for those who showed abnormality with the previous three tests. The frequency of coagulopathy in patients with isolated TBI is 8.3%. Brain edema is the most common CT finding in patients with coagulopathy following TBI as it is present in (80%) of case .SDH is the second most common CT finding in those who develop coagulopathy occurring in (60%) of patients. . All patients with coagulopathy had FDP >10 mic/ml and INR>1.3 ,while PTT >34 seconds in (80%) of patients who develop coagulopathy while platelets