REVIEW OF OF APIGENIN LOADED ANTI-INFLAMMATORY NANOGEL

Transdermal drug delivery systems provide an easy, reliable mechanism of administering drugs when rapid onset is not important. Transdermal drug delivery bypasses the enterohepatic circulation, thereby providing a more reliable clinical action. Nanogels are commonly used in sensing, diagnostics, and bioengineering, but they are also often used in drug delivery. Nanogels have benefits over conventional and macro-sized delivery systems because of their higher drug loading capacity, high stability, and improved contact time with the skin surface, which makes it more convenient as a transdermal drug delivery system. Nanogels composed of nanosize particles formed by physically or chemically cross linked polymer networks that swells in a good solvent. The nanogel systems have proven their potential to deliver drugs in controlled, constant and targetable mode. With the promising field of polymer sciences it has now become predestinated to prepare smart nano-system which can establish effectual for treatment, diagnosing as well as clinical trials progress. Keywords: Anti-inflammatory, Nanogel, Apigenin