This seurat object contains single cell RNAseq data of human pancreatic islets from 5 healthy donors published in Shrestha et al., JCI Insight 2021(https://doi.org/10.1172/jci.insight.151621). It contains profile of 40,000 cells from whole islet tissue post quality filters. Inferred cell types from this data include Alpha, Beta, Delta, Gamma, Epsilon, Acinar, Ductal, Endothelial, Stellate, Immune and are added to metadata column "CellTypes". Donor's age has been added to metadata column "Age"
BACKGROUND: Human pancreatic islets are a central focus of research in metabolic studies. Transcript...
SummaryTo understand organ function, it is important to have an inventory of its cell types and of t...
Summary: Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglyc...
Bulk data of human pancreas The dataset from Fadista et al. (2014) contains raw read counts data fr...
Pancreatic islets of Langerhans contain several specialized endocrine cell types, which are commonly...
This dataset is part of the manuscript Genetic risk converges on regulatory networks mediating early...
RNA sequencing of human pancreatic islets has provided important insights into the islet transcripto...
Background: The endocrine pancreas contains multiple cell types co-localized into clusters called t...
Detailed characterization of human pancreatic islets is key to elucidating the pathophysiology of al...
RNA sequencing of human pancreatic islets has provided important insights into the islet transcripto...
Detailed characterization of human pancreatic islets is key to elucidating the pathophysiology of al...
Additional file 3: Figure S1. Ambient contribution and islet cell gene marker UMAP and violin plots ...
Article corrigé dans Stem Cell Research & Therapy 2020 11:190 (DOI : 10.1186/s13287-020-01717-4)Int...
Pancreatic islets consist of multiple cell types that produce hormones required for glucose homeosta...
The ghrelin producing ε-cell represents the fifth endocrine cell type in human pancreatic islets. Th...
BACKGROUND: Human pancreatic islets are a central focus of research in metabolic studies. Transcript...
SummaryTo understand organ function, it is important to have an inventory of its cell types and of t...
Summary: Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglyc...
Bulk data of human pancreas The dataset from Fadista et al. (2014) contains raw read counts data fr...
Pancreatic islets of Langerhans contain several specialized endocrine cell types, which are commonly...
This dataset is part of the manuscript Genetic risk converges on regulatory networks mediating early...
RNA sequencing of human pancreatic islets has provided important insights into the islet transcripto...
Background: The endocrine pancreas contains multiple cell types co-localized into clusters called t...
Detailed characterization of human pancreatic islets is key to elucidating the pathophysiology of al...
RNA sequencing of human pancreatic islets has provided important insights into the islet transcripto...
Detailed characterization of human pancreatic islets is key to elucidating the pathophysiology of al...
Additional file 3: Figure S1. Ambient contribution and islet cell gene marker UMAP and violin plots ...
Article corrigé dans Stem Cell Research & Therapy 2020 11:190 (DOI : 10.1186/s13287-020-01717-4)Int...
Pancreatic islets consist of multiple cell types that produce hormones required for glucose homeosta...
The ghrelin producing ε-cell represents the fifth endocrine cell type in human pancreatic islets. Th...
BACKGROUND: Human pancreatic islets are a central focus of research in metabolic studies. Transcript...
SummaryTo understand organ function, it is important to have an inventory of its cell types and of t...
Summary: Type 2 diabetes mellitus (T2D) is a chronic age-related disorder characterized by hyperglyc...