An Unusual Case of Severe Vaccine Induced Immunologic Thrombocytopenia Purpura from Moderna SARS-CoV-2 Vaccination in an Immunocompromised Patient

Introduction: Immune Thrombocytopenia (ITP) is an autoimmune hematologic disorder characterized by destruction of platelets and decreased platelet production due to antibodies directed against platelet surface glycoproteins. ITP can be both primary with unknown etiology and secondary, presenting after viral illness, with concurrent autoimmune disease, or post vaccination. Severe secondary immune thrombocytopenia has been recorded after administration of both Pfizer and Moderna SARS-CoV-2 vaccination. Our goal is to alert clinicians to the relationship of de novo post-vaccination ITP after administration of the SARS-CoV-2 vaccines, specifically in immunosuppressed populations