EVALUATION OF ANTI ARTHRITIC ACTIVITY OF ETHANOLIC EXTRACT OF PELTOPHORUM PTEROCARPUM FLOWERS

Peltophorum pterocarpum belongs to the family caesalpiniaceae and traditionally it is proved to be used in the treatment of stomatitis, insomnia, constipation, ringworm, dysentery, muscular pains, sores and skin disorders. The objective of the study is to evaluate the antiarthritic activity of ethanolic extravt Peltophorum pterocarpum flowers by using protein denaturation method. The inhibition of protein denaturation was taken as a measure of the invitro anti-arthritic activity. The maximum percentage inhibition of protein denaturation for Peltophorum pterocarpum flower extracts were found to be 75.42±1.92%, 83.01±1.33% and 87.67±1.21% respectively at a dose of 600, 800, 1000 μg/ml. When compared to standard diclofenac sodium was found out to be 82.0±1.63%, 87.77±1.08% and 91.54±0.80% respectively at a dose of 600, 800, 1000 μg/ml. in conclusion the results support the use of ethanolic extravt Peltophorum pterocarpum flowers in treating arthritis