Dermatofibrosarcoma Protuberans (DFSP): An Uncommon Skin Cancer

Dermatofibrosarcoma Protuberans (DFSP) is a very uncommon type of skin cancer that begins in the connective tissues of skin and extend to nearby structures in the form of lump. The cause of cutaneous fibroids is unknown, although a suggested risk factor includes skin lesions at the affected site. DFSP tends to affect people between the age of 20 and 50, but it has been diagnosed in people of all ages. This case report describes a highly recurrent DFSP disease condition of 25 years old female, who got admitted in a tertiary care cancer centre with complaints of painless swelling in the back, fever, and loss of weight since last 1 month. Surgical history revealed three past surgical excisions of the mass over the same location. CT scan and tissue biopsy revealed recurrent Dermatofibrosarcoma protuberans. Initially, the patient was on imatinib 600 mg/PO/OD, after which there was a subjective decrease in size of mass. But as the patient was unable to tolerate high doses of imatinib, she then underwent wide local excision of the mass with split skin graft taken from right thigh under general anesthesia. Surgery was uneventful and she was discharged thereafter. As local recurrence is common, patients required close clinical follow-up after completing treatment