Modulating neuro-endocrine effects of bioactive water Naftussya from layers Truskavets' and Pomyarky at humans with dysfunction of neuro-endocrine-immune complex

Popovych Igor L, Sydoruk Nadiya O, Gozhenko Anatoliy I, Zukow Walery. Modulating neuro-endocrine effects of bioactive water Naftussya from layers Truskavets’ and Pomyarky at humans with dysfunction of neuro-endocrine-immune complex. Journal of Education, Health and Sport. 2017;7(2):465-478. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.437582 http://ojs.ukw.edu.pl/index.php/johs/article/view/4349 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.02.2017. Revised 12.02.2017. Accepted: 28.02.2017. MODULATING NEURO-ENDOCRINE EFFECTS OF BIOACTIVE WATER NAFTUSSYA FROM LAYERS TRUSKAVETS’ AND POMYARKY AT HUMANS WITH DYSFUNCTION OF NEURO-ENDOCRINE-IMMUNE COMPLEX Igor L Popovych1, Nadiya O Sydoruk2,3, Anatoliy I Gozhenko2, Walery Zukow4 1Department of Immunophysiology, OO Bogomoletz Institute of Physiology NAS, Kyiv, Ukraine i.popovych@biph.kiev.ua 2Ukrainian Scientific Research Institute of Transport Medicine Ministry of Health, Odesa Gozhenko@mail.ru 3JSC “Dnipro-Beskyd”, Truskavets’, Ukraine dnipro-b@bk.ru 4Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland w.zukow@ukw.edu.pl Abstracts Background. Previously we have been carry out comparative investigation long-term effects of Bioactive Water Naftussya from layers Truskavets’, Pomyarky and Skhidnyts’a on some metabolic and biophysical parameters at men with dysfunction of neuro-endocrine-immune complex. The aim of this study is the investigation long-term effects on neuro-endocrine regulation at similar patients. Materials and methods. The object of observation were 20 volunteers: ten women and ten men aged 33-76 years without clinical diagnose but with dysfunction of neuro-endocrine-immune complex and metabolism. We evaluated the trait and reactive anxiety, recorded EEG, HRV and blood pressure, determined levels of Cortisol, Aldosterone, Testosterone, Triiodothyronine and Calcitonin. After examination volunteers within 7 days used bioactive water Naftussya (250 mL three times a day) from Truskavets’ or Pomyarky layer, then repeated the tests listed. Results. Weekly drinking of Bioactive Water Naftussya normalizes initially elevated levels of testosterone in women and reduces initially normal its level in men, in both sexes normalizes initially elevated levels of triiodothyronine and activity of the autonomic regulatory systems as the parasympathetic, so sympathetic, combined with a slight increase in the normal levels of aldosterone and trend to increase (under low) reactive anxiety as well as post occlusive reactivity of vascular tone. Among the 164 registered parameters quantitative EEG revealed noticeable changes only 8. This is, above all, normalizing increase initially reduced spectral power density (SPD) α-rhythm in loci T6 by 93%, P4 by 33%, F7 by 29%, increase by 10% in the normal range modal frequency of β-rhythm and further enhance SPD θ-rhythm in locus T5 by 42%. On the other hand, showed a reduction by 28% initially normal PSD of β-rhythm in locus in O2 and further reduction its by 20% in locus P4. Moreover, there was left-sided lateralization initially symmetric α-rhythm. No significant differences between the effects of Naftussya both deposits were found. Conclusion. Bioactive water Naftussya both Truskavets’ and Pomyarky layers causes favorable normalizing effects on abnormalities neuro-endocrine parameters, which is a manifestation of its adaptogenic properties. Keywords: bioactive water Naftussya, adaptation hormones, HRV, EEG.Popovych Igor L, Sydoruk Nadiya O, Gozhenko Anatoliy I, Zukow Walery. Modulating neuro-endocrine effects of bioactive water Naftussya from layers Truskavets' and Pomyarky at humans with dysfunction of neuro-endocrine-immune complex. Journal of Education, Health and Sport. 2017;7(2):465-478. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.437582 http://ojs.ukw.edu.pl/index.php/johs/article/view/434