Inflammatory bowel disease in children

Putowski Maciej, Padala Olga, Krupa Adrianna, Konopelko Michał, Piasek Ewa, Mazurek Marek. Inflammatory bowel disease in children. Journal of Education, Health and Sport. 2019;9(8):406-411. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3379040 http://ojs.ukw.edu.pl/index.php/johs/article/view/7327 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.08.2019. Revised: 15.08.2019. Accepted: 27.08.2019. Inflammatory bowel disease in children Maciej Putowski, putowski.maciek@gmail.com ORCID:0000-0002-7575-2456 Department of Experimental Hematooncology, Medical University of Lublin, Chodźki 1 Street, 20- 093 Lublin, Poland Padała Olga, olga.padala@gmail.com ORCID:0000-0003-1469-0877 1st Department of Psychiatry, Psychotherapy and Early Intervention Medical University of Lublin, Gluska Street 1, 20-439 Lublin, Poland Krupa Adrianna, adriannakrp@gmail.com ORCID:0000-0003-0866-3952 Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4 Street, 20-090 Lublin, Poland Michał Konopelko, mm.konopelko@gmail.com ORCID:0000-0003-4103-7400 Department of Otolaryngology and Laryngological Oncology, Medical University of Lublin, Jaczewskiego 8, 20 954, Lublin, Poland Ewa Piasek, ewa.piasekk@gmail.com, ORCID:0000-0003-3344-4022 I Clinic of Anaesthesiology and Intensive Therapy, Medical University of Lublin, Jaczewskiego 8, 20 954, Lublin, Poland Mazurek Marek, marekmazurek@hotmail.com, ORCID:0000-0002-3121-7195 Chair and Department of Neurosurgery and Paediatric Neurosurgery Medical University of Lublin, Jaczewskiego 8, 20 954, Lublin, Poland Abstract Pediatric inflammatory bowel diseases (IBDs), including Crohn disease (CD) and ulcerative colitis (UC), are chronic relapsing inflammatory disorders of the gastrointestinal tract. The incidence and prevalence of IBD is increasing, and approximately 25% of all patients are diagnosed before the age of 18 years. The pathogenesis of IBD is not fully understood but is thought to be mediated by dysregulated mucosal immune response, microbial dysbiosis, genetic and environmental factors. The presentation of IBD, especially in children and adolescents is variable, including both gastrointestinal and extraintestinal manifestations. The recommended diagnostic procedures of choice are ileocolonoscopy and esophagogastroduodenoscopy. IBD are diagnosed by the combination of clinical, pathological, endoscopic and serological features. The aims of therapy in pediatric IBD is to induce and maintain clinical remission, relieve symptoms, optimize growth, improve quality of life, and minimize toxicity as much as possible. The ECCO/ESPGHAN consensus guidelines include exclusive enteral nutrition, corticosteroids, 5-aminosalicylates, immunomodulators, biologics and surgery. Key words: inflammatory bowel disease, Crohn disease, ulcerative coliti