Studies on the kinetics of tetrahexylammonium bromochromate oxidation of methionine in various percentage of acetic acid + N,N-dimethylformamide mixture

Post Graduate and Research Department of Chemistry, C. Abdul Hakeem College, Melvisharam-632 509, Tamilnadu, India E-mail : smansoors2000@yahoo.co.in Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia Manuscript received online 21 October 2012, revised 18 November 2012, accepted 19 November 2012 Abstract : Methionine (Met) is a naturally occurring sulphur containing amino acid. The kinetics of oxidation of methionine by tetrahexylammonium bromochromate (THexABC) in various percentage of acetic acid + N,N-dimethylformamide mixture (AcOH + DMF) leads to the formation of corresponding sulphoxide. The reaction Is first order each in Met, THexABC and [H+]. The reaction is catalysed by hydrogen ions. The reaction rate have been determined at different percentage of AcOH + DMF mixtures at different temperatures and activation parameters calculated. The reaction does not Induce polymerization of acrylonitrile. A suitable mechanism bas been proposed