Synthesis and Biological Activity of some New Quinazolinyl Thiazolidinones and Azetidinones

Department of Chemistry, Shivaji University, Kolhapur-416 004 Manuscript received 3 November 1992, revised 8 October 1993, accepted 18 April1994 Sequential treatment of anthranilic acid in pyridine with benzoyl chloride and hydrazine hydrate gives 2 that has been converted to azetidinones (4) and thiazolidinones (5) via the N-arylidene derivatives (3). Most of the compounds 4 and 5 showed moderate to good antimicrobial activity