Introduction: Cardiovascular diseases are currently the leading cause of global disability and mortality. According to the centers for disease control and prevention, the average life expectancy of a person would be 10 years longer but for a high prevalence of cardiovascular diseases, and if antiplatelet drugs and special therapy were used. Materials and methods: Antiplatelet activity of the novel benzimidazole derivatives containing a sterically hindered phenolic group in their structure has been investigated in vitro, using a model of ADP-induced platelet aggregation of rabbit's plasma. The compounds exhibiting high antiplatelet activity and acetylsalicylic acid, as a reference drug, were examined for antioxidant properti...
(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting ...
8BACKGROUND: Platelet aggregation plays a pathogenic role in the development of arterial thrombi, wh...
Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chr...
The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previou...
A growing number of researchers in the field of medicinal chemistry are focused on nitrogenous heter...
A growing number of researchers in the field of medicinal chemistry are focused on nitrogenous heter...
Cardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development ...
International audienceUNLABELLED: BACKGROUND: Thromboxane A2 is derived from arachidonic acid throug...
Cardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development ...
A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. This N-(bipheny...
Introduction: Biphenyl and imidazobenzimidazole derivatives attract ongoing attention as a combinati...
The role of blood components including platelets, in initiating inflammation, endothelial dysfunctio...
Despite the substantial clinical success of aspirin and clopidogrel in secondary prevention of ische...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72811/1/j.1527-3466.1994.tb00291.x.pd
Introduction:Cardiovascular and thromboembolic diseases are one of the most common causes of death i...
(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting ...
8BACKGROUND: Platelet aggregation plays a pathogenic role in the development of arterial thrombi, wh...
Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chr...
The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previou...
A growing number of researchers in the field of medicinal chemistry are focused on nitrogenous heter...
A growing number of researchers in the field of medicinal chemistry are focused on nitrogenous heter...
Cardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development ...
International audienceUNLABELLED: BACKGROUND: Thromboxane A2 is derived from arachidonic acid throug...
Cardiovascular diseases (CVD) are one of the main causes of mortality in the world. The development ...
A new series of non peptide angiotensin(A-II) receptor antagonist has been prepared. This N-(bipheny...
Introduction: Biphenyl and imidazobenzimidazole derivatives attract ongoing attention as a combinati...
The role of blood components including platelets, in initiating inflammation, endothelial dysfunctio...
Despite the substantial clinical success of aspirin and clopidogrel in secondary prevention of ische...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72811/1/j.1527-3466.1994.tb00291.x.pd
Introduction:Cardiovascular and thromboembolic diseases are one of the most common causes of death i...
(1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting ...
8BACKGROUND: Platelet aggregation plays a pathogenic role in the development of arterial thrombi, wh...
Thrombocytopenia is a major hematological concern in oxidative stress-associated pathologies and chr...