IMIDOCHLORIDES. PART IX. REACTION OF AROMATIC ANILIDE IMIDOCHLORIDES WITH ETHYL SODIOACETOACETATE: SYNTHESIS OF SOME 4-H YDROXY-2-ARYL-3.ACETVLQUINOLINES

Desai and Shah ( this Journal, 1949, 26. 121.) achieved the synthesis of otherwise inaccessible 4-hydroxy-2-phenyl-3- acetylquinolines by the condensation of benzanilide imidochlorides with ethyl sodiacetoacetate. In extension of this work imidochlorides derived from simple anilides of o-, m-, and p-toluic acids, m-, p-bromobenzoic acids, p-chlorobenzoic acid, a- and ß-naphthoic acids have been condensed with ethyl sodioacetoacetate, and the crude condensation products obtained were cyclised to the corresponding 4-hydroxy-2-aryl-3-acetylquinolines