THE EFFECTIVENESS OF PPI IN THE CURE OF LARYNGOPHARYNGEAL REFLUX

Objective: Laryngopharyngeal reflux (LPR) is the type of swelling. This disease affects a greater number of patients. The retrospective current of gastric stuffing addicted to pharynx and larynx is the major source of this disorder. Patients suffering from this disease show many indications. The objective of the revision is to recognize the effectiveness of PPI in the cure of LPR. Patients and Methods: The study was of forthcoming observational type. The study was made on 61 patients who were present in Mayo Hospital Lahore. The duration of the study was from January 2018 to July 2018. Patients continuously expressing the indications of laryngeal inflow for about 2 months were added in the study. Flexible naso-pharangoscope was used for laryngoscope observations. By observing the reflux symptoms index and reflux symptoms findings we can identify the complexity stage of the laryngeal symptoms. An esophagogastrodudenoscopy was performed in each patient before initiating the treatment. Results: 61 patients were added in the reading. The average age of the cases was between 31.62±5.61. 34.43% women and 65.57% men were added in the research. The regular weight of the females was 23±3.9 and that of males was 20±4.2. 54 patients were suffering from lump in the throat which was considered as common indication. The less frequent symptom is the complexity in breathing which was present in 21 patients. 20 mg dose of pantoprazole id given to the patient for healing two times in a day. This practice was carried out for about 6 months. The improvement in the indications was found after the treatment of 2 months on regular basis. The patients were recovered completely after 6 months regular treatment. In 54 patients the most general laryngeal finding is Erythema. 12 patients showed the presence of pseudosulcus. Some indications like endoscopic fractional ventricular annihilation, gentle choral cords edema, gentle laryngeal edema and perseverance of granuloma were also noticed after the completion of 6 months treatment. Conclusion: The laryngopharyngeal reflux indications can be eliminated or reduced by the use of 20 mg Pantoprazole two times in a day followed for about 6 months. Key Words: Proton Pump Inhibitors; Laryngopharyngeal Reflux; GER