Influence of antenatal hypoxia on coagulation properties of the blood in sexual mature rats

The paper presents the results of studies on the effects of hypoxia in the antenatal period on a number of blood coagulability indicators in adult rats. It was revealed that the long-term effect of prenatal hypoxia contributes to the acceleration of certain parameters of blood clotting. The established hypercoagulable shift in the system. It was shown that at the same time the blood coagulation time and recalcification accelerated; thromboplastic activity, prothrombin and thrombin time increased, and at the same time plasma high tolerance to heparin was noted. These studies suggest that prenatal hypoxia alters the overall state of blood coagulation, where it forms a qualitatively new stereotype of the relationship between hemocoagulation and fibrinolysis factors