A preliminary study on the effect of dose rate on 5-hydroxy-L-tryptophan, L-cysteine and cystamine

Institute of Neclear Medicine & Allied Sciences, Brig. S. K. Mazumdar Marg, Delhi-110 054, India Fax : 91-3919509 Manuscript received 20 February 2002, revised 26 July 2002. accepted 12 September 2002 Dose rate dependent expositions of chromophores like SH, COOH and NH2 occurred with L-cysteine (0.4 mM) that were detected by increase in absorbance intensity at absorbance maximum. Depletion of these chromophores as a function of increasing close of irradiation were detected by specific reagents. No significant dependence of dose rate on exposition of chromophores were observed with cystamine (1mM) But depletion of SH and NH2 groups as an increasing function of dose from it were confirmed by specific reagents. Dose rate dependency in the exposition of chromophores of 5-hydroxy-L-tryptophan \(\mu\)M) was observed. Depletion of NH2 and COOH groups with increasing radiation dose was confirmed by specific reagents