Cytokines: The Potential biomarker in Sepsis of dog

Sepsis is most important aetiological factor for death in dogs throughout the World. Various pathophysiological studies indicated that septic shock is occured due to inflammatory reaction that triggers cellular damage, multiorgan failure, and thereby, death. Cytokines have an immense role in causing immunological response through its pleiotropic activities. Generally, cytokines have both pro- as well as anti-inflammatory actions by maintaining regulatory defense mechanisms through counteracting with invading microorganisms. Cytokines are the important biomarker to unregulate the immunological functions by accelerating inflammation related to cellular damaging. In my present study, I correlate the potential role of cytokines in maintaining tissue-damaging activities in tissues in the dog