A Review of Herbal Treatment for Peptic Ulcer

ABSTRACT Peptic ulcer is caused by mucosal injury that penetrates through muscularis mucosal covering and forms a wound which is surrounded by acute and chronic inflammation. Peptic ulcer comprised of both duodenal and stomach ulcers. Peptic ulcer disease is an imbalance of protective mucosal blockage and aggressive gastric luminal factors like lipid peroxidation, nitric oxide and acid pepsin secretion. Standard treatments of peptic ulcers using H-2 (Histamine Receptor) antagonists and H+ pump inhibitors have shown drug interactions, mild to severe adverse effects, and also relapses in some cases. While the medicinal plants and their antiulcer phytoconstituent's are advantageous in treatment of peptic ulcer. There are so many plants which constitute have numerous floral products that have been turned up to possess antiulcer activity. Phytoconstituents like flavonoids, tannins, terpenoids, kaempferol etc. are useful in treating peptic ulcers. This review focusses on medicinal plants whose phytoconstituents have a gastroprotective role and thus they can be used for prevention or treatment of peptic ulcer. Keywords: antiulcer phytogenic compounds, proton pump inhibitor, botanical products, peptic ulce