THE IMPACT OF DEXMEDETOMIDINE AND REMIFENTANIL IN INTRAVENOUS ANAESTHESIA (IVAD) IN LAPAROSCOPIC CHOLECYSTECTOMY ACTIVITIES

Aim: The purpose was to analyze impact of dexmedetomidine and remifentanil in intravenous anaesthesia (IVAD) in laparoscopic cholecystectomy activities. Methods: This existing research was conducted at Mayo Hospital, Lahore from May 2018 to March 2019. The review involved patients aged 40 years, 19 to 63 years, who underwent elective laparoscopic cholecystectomy. In Group D, IVAT was performed using 160 mixtures of μg/kg/min propofol and 0.6 μg/kg/h dexmedetomidine. In Set R, TIVA was achieved through 160 μg/kg/min propofol and 0.6 μg/kg/min remifentanil. SBP, pulse, SpO2 and end-tidal CO2 were noted. Altogether mixtures were completed near end of the medical procedure. Adequate unconstrained breathing, extubation and response to verbal instructions; and Aldrete score ≥ several times, postoperative agony scores and basic limitations in postoperative phase were noted. A tolerant and controlled pain-free siphon was applied in each postoperative patient. All pain relief uses, patients' initial pain relief needs were noted. Results: Intraoperative systolic pulse, diastolic circulatory pressure and pulse degree remained lower overall in the remifentanil set associated to the dexmedetomidine set (p < 0.06). The first absence of postoperative pain remained shorter and hemodynamic limitations were basically higher in this group (p < 0.06). Postoperative recovery in the dexmedetomidine set was increasingly stable with respect to VAS estimation (p < 0.06). Conclusion: Remifentanil provides strong contrasting intraoperative anaesthesia and dexmedetomidine; in any case, dexmedetomidine could be measured in TIVA as the steady postoperative recovery option. Key words: Dexmedetomidine; Remifentanil; Total intravenous anesthesia; Hemodynamics; Retrieval; Discomfort