Interrelations between changes in parameters of HRV, EEG and phagocytosis at patients with chronic pyelonephritis and cholecystitis

Popovych Igor L, Kul’chyns’kyi Andriy B, Gozhenko Anatoliy I, Zukow Walery, Kovbasnyuk Marta M, Korolyshyn Tetyana A. Interrelations between changes in parameters of HRV, EEG and phagocytosis at patients with chronic pyelonephritis and cholecystitis. Journal of Education, Health and Sport. 2018;8(02):135-156. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1172164 http://ojs.ukw.edu.pl/index.php/johs/article/view/5280 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.01.2018. Revised: 10.01.2018. Accepted: 12.02.2018. Interrelations between changes in parameters of HRV, EEG and phagocytosis at patients with chronic pyelonephritis and cholecystitis Igor L Popovych1, Andriy B Kul’chyns’kyi2,3, Anatoliy I Gozhenko3, Walery Zukow4, Marta M Kovbasnyuk1, Tetyana A Korolyshyn1 1Department of Immunophysiology, OO Bohomolets’ Institute of Physiology, Kyїv, Ukraine i.popovych@biph.kiev.ua 2Communal Hospital, Truskavets’, Ukraine akul@i.ua 3Ukrainian Scientific Research Institute of Transport Medicine, Odesa prof.gozhenko@gmail.com 4Nicolaus Copernicus University, Torun’, Poland w.zukow@wp.pl Abstract Background. Previously we have shown within the immunological homunculus conception that take place causal relationships between induced by balneotherapy changes in parameters of EEG and HRV, on the one hand, and the parameters of humoral and cellular immunity, on the other hand. The purpose of this study is to find out the relationships between induced by balneotherapy changes in parameters of EEG and HRV, on the one hand, and the parameters of phagocytosis, on the other hand. Material and methods. In basal conditions in 33 men and 10 women with chronic pyelonephritis and cholecystitis in remission, we recorded twice, before and after balneotherapy at the spa Truskavets’, EEG (“NeuroCom Standard”) and HRV (“Cardiolab+VSR”). In blood estimated parameters of phagocytic function of neutrophils against Staphylococcus aureus and Escherichia coli. Results. Judging by the coefficients of canonical correlation, the maximal subordinate nervous regulation is the completeness of phagocytosis of E. coli (R=0,944), whereas the influence of the nervous system on the completeness of phagocytosis Staph. aur. is minimal (R=0,607). With regard to the intensity of phagocytosis, the differences in the strength of nerve influence are expressed less (0,893 vs 0,744), and in relation to the activity of phagocytosis as well as the bactericidal ability of neutrophils, there are no differences between R (0,858 vs 0,857 and 0,831 vs 0,834, respectively). However, significant differences were found between profiles of correlation coefficients between EEG and HRV parameters, on the one hand, and phagocytosis parameters, on the other hand, for representatives of Gram-negative and Gram-positive microbes. Conclusion. In the nervous regulation of phagocytosis by neutrophils of the Gram-negative and Gram-positive microbes are involved the structures that are localized in different parts of the CNS. Keywords: EEG, HRV, neutrophils, phagocytosis, Staphylococcus aureus, Escherichia coli