A Systematic Review & Meta-Analysis on Interrelating Comorbid Conditions and Breathing Practices

Background & Objective: Previous studies have suggested that there is a correlation between cardiovascular and respiratory disorders. The current review was carried out to comprehensively examine the probable relationship between cardiovascular disorder, respiratory disorder, and breathing habits by locating all relevant research & combining their findings. Methods: A literature search on PubMed, Science Direct databases was performed on past 10 years data. For randomized controlled trials (RCT) studies included cardiovascular & respiratory disorder and accumulated data on breathing practices. The modified Jadad scale was used to evaluate the quality of the evidence. The random effect model was used to compute the mean difference (MD), standardised mean difference (SMD), and 95% confidence interval (CI) for the continuous outcome. Results: A total of 20 RCT studies with 1,333 participants with age group of 18-85 years were included in these studies. On the basis of heterogeneity breathing practices showed a positive effect on respiratory disorder in COPD (SMD = -0.29,95%CI: -0.74, -0.15) than low positive effect on cardiovascular disorder (SMD = -0.24,95%CI: -0.48, -0.55). The assessed quality of the studies based on the modified Jadad scale was high (5.2). Conclusion: In current systematic review & meta -analysis found to discover the correlation between respiratory diseases (COPD & asthma) and cardiovascular diseases (hypertension) and breathing practices. The outcome of the systematic review and meta-analysis conformed that breathing exercises are more effective for the adult age group over 26 years for cardiovascular and respiratory diseases.http://impactfactor.org/PDF/IJCPR/14/IJCPR,Vol14,Issue4,Article6.pd