Detection of Antibiotic Resistance of Pathogenic Bacteria Recovered from Cutaneous Lesions of Human Leishmaniasis Patients in Khartoum State (Sudan)

The purpose of this work was to investigate the presence of pathogenic bacteria in lesions of patients with cutaneous leishmaniasis wounds and the pattern of susceptibility to antibiotics, in order to study the prevalence of secondary bacterial infection in ulcerated lesions and its relationship to the healing process. Twenty samples from leishmaniotic patients attended at the Institute of Endemic Diseases-University of Khartoum were evaluated. The criteria for inclusion of patients in this work were based on a positive clinical diagnosis of CL ulcer together with laboratory analysis. The bacteria isolated were Staphylococcus aureus in 9 cases (45%), coagulase negative Staphylococcus in 11 cases (55%). Forty four percent of the S. aureus were resistant to methicillin and vancomycin, 56% to erythromycin, and 78% to amoxicillin. 45% of the coagulase negative Staphylococci were resistant to methicillin, 55% to vancomycin and amoxicillin. All the Staphylococcus isolates were highly sensitive to meropenem and amikacin (99-100%)