Stereospecific β-lactam formation via Staudinger cycloaddition derived from ferrocenyl imines

Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd. Houston, TX 77030, USA Department of Chemistry, The University of Texas-Pan American, 1250 West University Drive, Edinburg, Texas 78539, USA Current address: Community Health Systems of South Texas, 3135 South Sugar Road, Edinburg, Texas 78539, USA E-mail: bimalbanik10@gmail.com, bimal.banik@chsst.org Manuscript received 01 July 2018, accepted 19 July 2018 Stereospecific synthesis of a few 3,4-disubstitued β-lactams derived from polyaromatic ferrocenyl imines is achieved follow­ing Staudinger cycloaddition reaction. The exclusive formation of trans-β-lactams is observed. The stereochemistry of these resulting β-lactams formation reaction is unprecedented