Relationships between caused by drinking of bioactive water Naftussya changes in urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities

Flyunt Viktor R, Flyunt Igor-Severyn S, Fil’ Vitalij M, Kovbasnyuk Marta M, Hryvnak Rostyslav F, Popel Svitlana L, Zukow Walery. Relationships between caused by drinking of bioactive water Naftussya changes in urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities. Journal of Education, Health and Sport. 2017;7(3):11-30. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.261918 http://ojs.ukw.edu.pl/index.php/johs/article/view/4203 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016). 754 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.01.2017. Revised 21.01.2017. Accepted: 26.01.2017. RELATIONSHIPS BETWEEN CAUSED BY DRINKING OF BIOACTIVE WATER NAFTUSSYA CHANGES IN URINE LITHOGENICITY AND NEURO-HUMORAL-IMMUNE FACTORS IN HUMANS WITH THEIRS ABNORMALITIES Viktor R Flyunt1,2, Igor-Severyn S Flyunt3, Vitalij M Fil’3, Marta M Kovbasnyuk2, Rostyslav F Hryvnak4, Svitlana L Popel4, Walery Zukow5 1JSC “Dnipro-Beskyd”, Truskavets’, Ukraine fliunt66@mail.ru 2Department of Immunophysiology, OO Bohomolets’ Institute of Physiology, Kyїv, Ukraine marta.kovbasnyuk@yandex.ua 3Department of Anatomy, Physiology and Valeology, Ivan Franko Pedagogical University, Drohobych, Ukraine iflyunt@bk.ru fillvitalij@rambler.ru 4JSC “ Truskavets’kurort”, Truskavets’, Ukraine 5Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland w.zukow@ukw.edu.pl SUMMARY Objective. Spa Truskavets' (Ukraine) considered to be indicated for the treatment and metaphylaxis renal stone disease. However, data on the effect of balneotherapy on the parameters of urine Lithogenicity ambiguous. This is due, perhaps, ambiguous influence balneotherapy on the neuroendocrine factors regulating exchange of electrolytes and uric acid. Aim: to find out the influence drinking of bioactive water Naftussya on urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities. Methods. The object of observation were ten women and ten men aged 33-76 years without clinical diagnose but with dysfunction of neuro-endocrine-immune complex and metabolism. In daily urine and blood we determined the content of electrolytes and nitrogenous metabolites, estimated parameters of immunity, recorded conductivity of acupuncture points and heart rate variability (HRV). After examination volunteers within 7 days used bioactive water Naftussya (250 ml three times a day), then repeated the tests listed. Results. Lithogenicity urine Index (Lith) calculated by formula: Lith=(Uric acid•Calcium/Magnesium•Creatinine)0,25. In 3 people initial normal Lith (0,65÷0,81 units) increased by 0,08÷0,16 units. In 4 people with normal or high Lith its changes were not detected (-0,01÷+0,01). In 12 people from a wide range of primary Lith (0,62÷1,07) it lowered by 0,03÷0,12 un. Even in a man maximum level of Lith (1,45 un.) down to the upper limit of normal (0,84 un.). Found a strong correlation between changes in Lith and a number parameters of HRV, metabolism and immunity. Conclusion. The use of bioactive water Naftussya causes ambiguous changes in Lithogenicity of urine, related to ambiguous changes in HRV, metabolism and immunity. Keywords: lithogenicity of urine, HRV, phagocytose, immunity, bioactive water Naftussya, spa Truskavets’.Flyunt Viktor R, Flyunt Igor-Severyn S, Fil' Vitalij M, Kovbasnyuk Marta M, Hryvnak Rostyslav F, Popel Svitlana L, Zukow Walery. Relationships between caused by drinking of bioactive water Naftussya changes in urine lithogenicity and neuro-humoral-immune factors in humans with theirs abnormalities. Journal of Education, Health and Sport. 2017;7(3):11-30. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.261918 http://ojs.ukw.edu.pl/index.php/johs/article/view/420