Supplemental material to the study "β subunits of GABAA receptors form proton-gated chloride channels: Insights into the molecular basis", published in Communications Biology. The upload contains the raw electrophysiology data as well as Molecular Dynamics simulation data. Two simulations systems were created containing the GABAA channel harbouring a protonated and deprotonated H267, respectively. For each system, a compressed Gromacs trajectory containing the concatenated MD data (.xtc), a representative conformation (.pdb) and a .tpr file have been uploaded
Recent disclosure of high resolution crystal structures of <i>Gloeobacter violaceus</i> (GLIC) in op...
Cys-loop receptors are membrane proteins that are key players for the fast synaptic neurotransmissio...
Understanding the intricate motions and conformational changes that govern biological processes rema...
<p>(A) Each GABAA receptor (or Cys-loop LGIC) subunit has the same topology, with a large extracellu...
Data to the paper "Subunit gating resulting from individual protonation events in Kir2 channels" acc...
These are the raw MD simulation data (water, ions and lipid removed) entitling the publication of "S...
Recent disclosure of high resolution crystal structures of Gloeobacter violaceus (GLIC) in open stat...
γ-Aminobutyric acidA (GABAA) receptors are members of the ligand-gated ion channel superfamily. They...
Two main projects involving molecular dynamics simulation of GABAAR and a collaborative project invo...
Ionotropic glutamate receptors, a family of ligand gated ion channels, are located in the post-synap...
We have developed a homology model of the GABAA receptor, using the subunit combination of α1β2γ2, t...
When γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrate brain, binds to...
The pentameric ligand-gated ion channel (pLGIC) superfamily, from bacteria to the brain, convert che...
AbstractWe have developed a homology model of the GABAA receptor, using the subunit combination of α...
STRUCTURAL INVESTIGATIONS OF LIGAND GATED ION CHANNELS Swarna Ramaswamy, B.S Advisor: Vasanthi Jayar...
Recent disclosure of high resolution crystal structures of <i>Gloeobacter violaceus</i> (GLIC) in op...
Cys-loop receptors are membrane proteins that are key players for the fast synaptic neurotransmissio...
Understanding the intricate motions and conformational changes that govern biological processes rema...
<p>(A) Each GABAA receptor (or Cys-loop LGIC) subunit has the same topology, with a large extracellu...
Data to the paper "Subunit gating resulting from individual protonation events in Kir2 channels" acc...
These are the raw MD simulation data (water, ions and lipid removed) entitling the publication of "S...
Recent disclosure of high resolution crystal structures of Gloeobacter violaceus (GLIC) in open stat...
γ-Aminobutyric acidA (GABAA) receptors are members of the ligand-gated ion channel superfamily. They...
Two main projects involving molecular dynamics simulation of GABAAR and a collaborative project invo...
Ionotropic glutamate receptors, a family of ligand gated ion channels, are located in the post-synap...
We have developed a homology model of the GABAA receptor, using the subunit combination of α1β2γ2, t...
When γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrate brain, binds to...
The pentameric ligand-gated ion channel (pLGIC) superfamily, from bacteria to the brain, convert che...
AbstractWe have developed a homology model of the GABAA receptor, using the subunit combination of α...
STRUCTURAL INVESTIGATIONS OF LIGAND GATED ION CHANNELS Swarna Ramaswamy, B.S Advisor: Vasanthi Jayar...
Recent disclosure of high resolution crystal structures of <i>Gloeobacter violaceus</i> (GLIC) in op...
Cys-loop receptors are membrane proteins that are key players for the fast synaptic neurotransmissio...
Understanding the intricate motions and conformational changes that govern biological processes rema...