Drug repositioning is a useful way to discover new drug candidates for curing diseases. However, integrating multiple networks and text mining information for drug repositioning is still a major challenge. We propose a drug repositioning method based on heterogeneous networks and text mining (HeTDR), which can combine drug features from multiple networks and disease features from biomedical corpora for drug repositioning. HeTDR obtains high accuracy in predicting drug-disease interactions and is capable of finding novel indications of approved drugs.More details can be found at: https://github.com/stjin-XMU/HeTD
Drug development is both increasing in cost whilst decreasing in productivity. There is a general ac...
Abstract. Drug repositioning helps identify new indications for marketed drugs and clinical candidat...
Drug repositioning offers new clinical indications for old drugs. Recently, many computational appro...
Abstract: Drug repositioning is a compelling technique to find new signs for existing medications. D...
New drug development is a time-consuming, high-investment, and high-risk process. It usually takes m...
Background: Given the costly and time consuming process and high attrition rates in drug discovery a...
Drug repositioning offers an effective solution to drug discovery, saving both time and resources by...
Abstract Background Although drug discoveries can provide meaningful insights and significant enhanc...
Current research and development approaches to drug discovery have become less fruitful and more cos...
Existing computational methods for drug repositioning either rely only on the gene expression respon...
Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drug...
Abstract Background Drug repositioning is the process of identifying new uses for existing drugs. Co...
As the amount of the publicly available scientific literature increases, efficient text mining techn...
Drug repositioning can reduce the time, costs and risks of drug development by identifying new thera...
Drug repositioning, an innovative therapeutic application of an old drug, has received much attentio...
Drug development is both increasing in cost whilst decreasing in productivity. There is a general ac...
Abstract. Drug repositioning helps identify new indications for marketed drugs and clinical candidat...
Drug repositioning offers new clinical indications for old drugs. Recently, many computational appro...
Abstract: Drug repositioning is a compelling technique to find new signs for existing medications. D...
New drug development is a time-consuming, high-investment, and high-risk process. It usually takes m...
Background: Given the costly and time consuming process and high attrition rates in drug discovery a...
Drug repositioning offers an effective solution to drug discovery, saving both time and resources by...
Abstract Background Although drug discoveries can provide meaningful insights and significant enhanc...
Current research and development approaches to drug discovery have become less fruitful and more cos...
Existing computational methods for drug repositioning either rely only on the gene expression respon...
Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drug...
Abstract Background Drug repositioning is the process of identifying new uses for existing drugs. Co...
As the amount of the publicly available scientific literature increases, efficient text mining techn...
Drug repositioning can reduce the time, costs and risks of drug development by identifying new thera...
Drug repositioning, an innovative therapeutic application of an old drug, has received much attentio...
Drug development is both increasing in cost whilst decreasing in productivity. There is a general ac...
Abstract. Drug repositioning helps identify new indications for marketed drugs and clinical candidat...
Drug repositioning offers new clinical indications for old drugs. Recently, many computational appro...